New treatment for bipolar depression could have fewer side effects

By Vivian Sum “People who come to us have symptoms so severe that they are not able to enjoy their life, work or relationships,” says Vancouver Coastal Health Research Institute clinician-scientist Dr. Fidel Vila-Rodriguez. Vila-Rodriguez is leading the Vancouver arm of a clinical trial investigating magnetic seizure therapy (MST) to treat bipolar depression. The study—which is also recruiting patients in Toronto and London, Ontario—will compare the effectiveness and side effects of MST with the current electroconvulsive therapy (ECT) approach. Results from the first randomized, double-blind study of its kind could lead to changes in how very severe cases of bipolar depression are treated. “When we see patients, they have invariably already tried other treatments for their bipolar depression, such as psychotherapy and

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