The accumulation of senescent cells with age is one of the root causes of aging. Senescent cells never amount to more than a few percent of all cells, even in late life, but they secrete a mix of extracellular vesicles and various proteins that is inflammatory and disruptive to tissue function. This is known as the senescence-associated secretory phenotype, or SASP. Since senescent cells inflect harm through signaling, it doesn’t take many such cells to act as a contributing cause of age-related disease and organ dysfunction. The research community is nowadays fully invested in the concept that senescent cells are a meaningful cause of aging. This is a comparatively recent development, despite the fact that the evidence was sizable and evident for several decades. It
from http://besthealthnews.com/2019/07/both-extracellular-vesicles-and-secreted-proteins-can-spread-cellular-senescence/
from
https://healthnews010.tumblr.com/post/186204318218
No comments:
Post a Comment