Discussing the DNA Damage Hallmark of Aging at Long Long Life

The Long Long Life team will be putting together a set of videos in the months ahead, one for each of the Hallmarks of Aging. The first to be published covers the hallmark of DNA damage, stochastic mutational change to nuclear DNA that is widely thought to make a meaningful contribution to the dysregulation of cell behavior in aging. This is evidently the case for cancer risk, as cancer is caused by mutations that enable rampant, unregulated growth, but may only be important otherwise when mutations occur in stem cells or progenitor cells that are able to propagate the mutations widely in tissues. The Hallmarks of Aging is a list of common processes and outcomes found in aging, and considered by a sizable fraction of the research

from https://www.fightaging.org/archives/2019/06/discussing-the-dna-damage-hallmark-of-aging-at-long-long-life/

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